Eosinopenia after Rabies Vaccine in dogs

The FDA has received 59 reports of eosinopenia in dogs after Rabies Vaccine. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

59Reports

95%Marked serious

12%Recovered

37%Died or euthanised

13 daysTypical onset

How soon it started

Same day

10 19%

1–2 days

5 9.6%

3–7 days

9 17%

1–4 weeks

12 23%

Over a month

16 31%

How the animals did

Recovered

6 10%

Recovered with lasting effects

1 1.7%

Still unwell when reported

22 37%

Died

11 19%

Euthanised

11 19%

Not known

8 14%

Problems reported at the same time

37 63%

36 61%

32 54%

30 51%

27 46%

27 46%

26 44%

24 41%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause eosinopenia in dogs?: 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eosinopenia with similar medicines

Eosinopenia after Bordetella Vaccine 68 reports · 0.7% of its reports
Eosinopenia after Leptospirosis Vaccine 60 reports · 0.7% of its reports
Eosinopenia after Distemper-parvo Vaccine 46 reports · 0.7% of its reports

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with eosinopenia