Dehydration after Leptospirosis Vaccine in dogs

The FDA has received 183 reports of dehydration in dogs after Leptospirosis Vaccine. That is 2.3% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

183Reports

81%Marked serious

12%Recovered

35%Died or euthanised

3 daysTypical onset

How soon it started

Same day

45 29%

1–2 days

33 21%

3–7 days

15 9.6%

1–4 weeks

24 15%

Over a month

39 25%

How the animals did

Recovered

22 12%

Still unwell when reported

70 38%

Died

21 11%

Euthanised

43 23%

Not known

27 15%

Problems reported at the same time

117 64%

116 63%

108 59%

87 48%

65 36%

64 35%

56 31%

51 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause dehydration in dogs?: 183 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dehydration with similar medicines

Dehydration after Rabies Vaccine 195 reports · 2.0% of its reports
Dehydration after Bordetella Vaccine 203 reports · 2.2% of its reports
Dehydration after Lyme Vaccine 43 reports · 0.6% of its reports
Dehydration after Distemper-parvo Vaccine 146 reports · 2.3% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with dehydration