Decreased urine concentration after Leptospirosis Vaccine in dogs

51 reports to the FDA describe decreased urine concentration in dogs given Leptospirosis Vaccine. That is 0.6% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

51Reports
65%Marked serious
9.8%Recovered
22%Died or euthanised
14 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
8 22%
1–2 days
3 8.1%
3–7 days
4 11%
1–4 weeks
10 27%
Over a month
12 32%

How the animals did

Recovered
4 7.8%
Recovered with lasting effects
1 2.0%
Still unwell when reported
31 61%
Died
3 5.9%
Euthanised
8 16%
Not known
4 7.8%

Problems reported at the same time

Loss of appetite
28 55%
Kidney problems
27 53%
Excessive thirst
27 53%
Vomiting
22 43%
Liver problems
20 39%
Excessive urination
19 37%
Lethargy
19 37%
Proteinuria
17 33%

Age of the animals

Under 1 year
5
1–3 years
3
4–7 years
14
8–11 years
16
12+ years
13

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause decreased urine concentration in dogs?
51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased urine concentration with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with decreased urine concentration