Cardiac arrest after Leptospirosis Vaccine in dogs

37 reports to the FDA describe cardiac arrest in dogs given Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

37Reports

100%Marked serious

0.0%Recovered

97%Died or euthanised

2 daysTypical onset

How soon it started

Same day

13 41%

1–2 days

4 13%

3–7 days

5 16%

1–4 weeks

2 6.3%

Over a month

8 25%

How the animals did

Died

34 92%

Euthanised

2 5.4%

Not known

1 2.7%

Problems reported at the same time

35 95%

16 43%

15 41%

13 35%

10 27%

10 27%

10 27%

7 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause cardiac arrest in dogs?: 37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cardiac arrest with similar medicines

Cardiac arrest after Rabies Vaccine 45 reports · 0.5% of its reports
Cardiac arrest after Bordetella Vaccine 41 reports · 0.4% of its reports
Cardiac arrest after Distemper-parvo Vaccine 33 reports · 0.5% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with cardiac arrest