Blood in vomit after Leptospirosis Vaccine in dogs

The FDA has received 69 reports of blood in vomit in dogs after Leptospirosis Vaccine. That is 0.9% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

69Reports

83%Marked serious

20%Recovered

19%Died or euthanised

Same dayTypical onset

How soon it started

Same day

33 51%

1–2 days

11 17%

3–7 days

3 4.6%

1–4 weeks

8 12%

Over a month

10 15%

How the animals did

Recovered

14 20%

Still unwell when reported

33 48%

Died

8 12%

Euthanised

5 7.2%

Not known

9 13%

Problems reported at the same time

31 45%

30 43%

25 36%

23 33%

20 29%

18 26%

13 19%

11 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause blood in vomit in dogs?: 69 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in vomit with similar medicines

Blood in vomit after Rabies Vaccine 71 reports · 0.7% of its reports
Blood in vomit after Bordetella Vaccine 95 reports · 1.0% of its reports
Blood in vomit after Distemper-parvo Vaccine 35 reports · 0.5% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with blood in vomit