Abnormal ultrasound finding after Leptospirosis Vaccine in dogs

The FDA has received 157 reports of abnormal ultrasound finding in dogs after Leptospirosis Vaccine. That is 2.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports
89%Marked serious
8.9%Recovered
42%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
38 31%
1–2 days
10 8.3%
3–7 days
13 11%
1–4 weeks
22 18%
Over a month
38 31%

How the animals did

Recovered
14 8.9%
Still unwell when reported
57 36%
Died
19 12%
Euthanised
47 30%
Not known
20 13%

Problems reported at the same time

Lethargy
95 61%
Vomiting
94 60%
Liver problems
91 58%
Loss of appetite
90 57%
Death
65 41%
Kidney problems
62 39%
Blood problems
58 37%
Diarrhea
42 27%

Age of the animals

Under 1 year
14
1–3 years
24
4–7 years
47
8–11 years
50
12+ years
22

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause abnormal ultrasound finding in dogs?
157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with abnormal ultrasound finding