Abnormal cytology after Leptospirosis Vaccine in dogs

97 reports to the FDA describe abnormal cytology in dogs given Leptospirosis Vaccine. That is 1.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports
57%Marked serious
12%Recovered
12%Died or euthanised
17 daysTypical onset
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How soon it started

Same day
11 14%
1–2 days
9 12%
3–7 days
14 18%
1–4 weeks
23 29%
Over a month
21 27%

How the animals did

Recovered
12 12%
Still unwell when reported
49 51%
Died
6 6.2%
Euthanised
6 6.2%
Not known
24 25%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
24
4–7 years
33
8–11 years
23
12+ years
8

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause abnormal cytology in dogs?
97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 17 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal cytology with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with abnormal cytology