Abdominal effusion after Leptospirosis Vaccine in dogs

The FDA has received 34 reports of abdominal effusion in dogs after Leptospirosis Vaccine. That is 0.4% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports

97%Marked serious

5.9%Recovered

59%Died or euthanised

10 daysTypical onset

How soon it started

Same day

5 17%

1–2 days

3 10%

3–7 days

4 14%

1–4 weeks

10 34%

Over a month

7 24%

How the animals did

Recovered

2 5.9%

Still unwell when reported

10 29%

Died

6 18%

Euthanised

14 41%

Not known

2 5.9%

Problems reported at the same time

Loss of appetite

23 68%

Abnormal ultrasound finding

21 62%

20 59%

20 59%

18 53%

17 50%

16 47%

12 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause abdominal effusion in dogs?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abdominal effusion with similar medicines

Abdominal effusion after Bordetella Vaccine 22 reports · 0.2% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with abdominal effusion