Liver problems after Estriol in dogs

116 reports to the FDA describe liver problems in dogs given Estriol. That is 5.7% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

116Reports
74%Marked serious
12%Recovered
14%Died or euthanised
32 daysTypical onset
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How soon it started

Same day
7 14%
1–2 days
4 8.0%
3–7 days
2 4.0%
1–4 weeks
10 20%
Over a month
27 54%

How the animals did

Recovered
9 7.8%
Recovered with lasting effects
5 4.3%
Still unwell when reported
54 47%
Died
3 2.6%
Euthanised
13 11%
Not known
32 28%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
6
4–7 years
12
8–11 years
50
12+ years
47

About this medicine

Type: medicine.

Questions owners ask

Can Estriol cause liver problems in dogs?
116 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 32 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Estriol in dogs · Medicines most reported with liver problems