Kidney problems after Estriol in dogs

101 reports to the FDA describe kidney problems in dogs given Estriol. That is 5.0% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

101Reports
78%Marked serious
6.9%Recovered
25%Died or euthanised
50 daysTypical onset
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How soon it started

Same day
8 15%
1–2 days
2 3.6%
3–7 days
3 5.5%
1–4 weeks
10 18%
Over a month
32 58%

How the animals did

Recovered
1 1.0%
Recovered with lasting effects
6 5.9%
Still unwell when reported
44 44%
Died
4 4.0%
Euthanised
21 21%
Not known
25 25%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
7
4–7 years
11
8–11 years
29
12+ years
53

About this medicine

Type: medicine.

Questions owners ask

Can Estriol cause kidney problems in dogs?
101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 50 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Estriol in dogs · Medicines most reported with kidney problems