Kidney problems after Cyclosporine (Atopica) in dogs

411 reports to the FDA describe kidney problems in dogs given Cyclosporine. That is 2.7% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

411Reports

36%Marked serious

4.1%Recovered

29%Died or euthanised

42 daysTypical onset

How soon it started

Same day

6 5.8%

1–2 days

6 5.8%

3–7 days

16 16%

1–4 weeks

19 18%

Over a month

56 54%

How the animals did

Recovered

10 2.4%

Recovered with lasting effects

7 1.7%

Still unwell when reported

73 18%

Died

82 20%

Euthanised

39 9.5%

Not known

200 49%

Problems reported at the same time

171 42%

157 38%

147 36%

142 35%

121 29%

90 22%

87 21%

64 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

101

8–11 years

147

12+ years

106

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause kidney problems in dogs?: 411 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 42 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Oclacitinib (Apoquel) 981 reports · 3.4% of its reports
Kidney problems after Ilunocitinib (Zenrelia) 86 reports · 3.9% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with kidney problems