Diarrhea after Cyclosporine (Atopica) in dogs

2,779 reports to the FDA describe diarrhea in dogs given Cyclosporine. That is 18% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

2,779Reports

24%Marked serious

19%Recovered

4.7%Died or euthanised

4 daysTypical onset

How soon it started

Same day

231 31%

1–2 days

108 14%

3–7 days

93 12%

1–4 weeks

110 15%

Over a month

213 28%

How the animals did

Recovered

523 19%

Recovered with lasting effects

7 0.3%

Still unwell when reported

284 10%

Died

91 3.3%

Euthanised

41 1.5%

Not known

1,833 66%

Problems reported at the same time

1,519 55%

592 21%

519 19%

249 9.0%

135 4.9%

134 4.8%

131 4.7%

108 3.9%

Age of the animals

Under 1 year

1–3 years

539

4–7 years

1,003

8–11 years

803

12+ years

334

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause diarrhea in dogs?: 2,779 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

Diarrhea after Oclacitinib (Apoquel) 2,589 reports · 8.9% of its reports
Diarrhea after Ilunocitinib (Zenrelia) 263 reports · 12% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with diarrhea