Cyclosporine (Atopica) side effects in dogs

15,302 reports sent to the FDA between 1995 and 2026 involve Cyclosporine in dogs. The most reported problems were vomiting, diarrhea, lethargy. 25% were marked serious, and where it was recorded, signs eased after stopping the medicine in 40% of cases.

15,302Reports
25%Marked serious
75%Only medicine involved
18%Recovered
5.0%Died or euthanised
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
15 0.1%
Didn't prevent heartworm
13 0.1%
Didn't stop ticks
2 0.0%

How soon problems started

Same day
1,239 29%
1–2 days
348 8.2%
3–7 days
308 7.2%
1–4 weeks
687 16%
Over a month
1,682 39%

Time from the first dose to the first sign, where both dates were reported (4,264 reports).

How the animals did

Recovered
2,651 17%
Recovered with lasting effects
117 0.8%
Still unwell when reported
1,829 12%
Died
490 3.2%
Euthanised
278 1.8%
Not known
9,937 65%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other anti-itch medicines for dogs