Blood problems after Cyclosporine (Atopica) in dogs

440 reports to the FDA describe blood problems in dogs given Cyclosporine. That is 2.9% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

440Reports

48%Marked serious

5.7%Recovered

37%Died or euthanised

18 daysTypical onset

How soon it started

Same day

14 8.4%

1–2 days

15 9.0%

3–7 days

28 17%

1–4 weeks

43 26%

Over a month

67 40%

How the animals did

Recovered

19 4.3%

Recovered with lasting effects

6 1.4%

Still unwell when reported

82 19%

Died

84 19%

Euthanised

80 18%

Not known

169 38%

Problems reported at the same time

184 42%

181 41%

171 39%

166 38%

151 34%

116 26%

98 22%

90 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

141

8–11 years

159

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause blood problems in dogs?: 440 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

Blood problems after Oclacitinib (Apoquel) 998 reports · 3.4% of its reports
Blood problems after Ilunocitinib (Zenrelia) 169 reports · 7.7% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with blood problems