Hypoalbuminaemia after Cyclosporine (Atopica) in dogs

204 reports to the FDA describe hypoalbuminaemia in dogs given Cyclosporine. That is 1.3% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

204Reports

21%Marked serious

3.4%Recovered

23%Died or euthanised

20 daysTypical onset

How soon it started

Same day

4 10%

1–2 days

3 7.7%

3–7 days

6 15%

1–4 weeks

8 21%

Over a month

18 46%

How the animals did

Recovered

5 2.5%

Recovered with lasting effects

2 1.0%

Still unwell when reported

31 15%

Died

32 16%

Euthanised

14 6.9%

Not known

120 59%

Problems reported at the same time

87 43%

76 37%

70 34%

69 34%

68 33%

63 31%

53 26%

51 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause hypoalbuminaemia in dogs?: 204 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

Hypoalbuminaemia after Oclacitinib (Apoquel) 424 reports · 1.5% of its reports
Hypoalbuminaemia after Ilunocitinib (Zenrelia) 53 reports · 2.4% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with hypoalbuminaemia