Hyperphosphataemia after Cyclosporine (Atopica) in dogs

The FDA has received 75 reports of hyperphosphataemia in dogs after Cyclosporine. That is 0.5% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

75Reports

25%Marked serious

1.3%Recovered

36%Died or euthanised

66 daysTypical onset

How soon it started

Same day

3 20%

1–2 days

0 0.0%

3–7 days

0 0.0%

1–4 weeks

4 27%

Over a month

8 53%

How the animals did

Recovered

1 1.3%

Still unwell when reported

9 12%

Died

20 27%

Euthanised

7 9.3%

Not known

38 51%

Problems reported at the same time

53 71%

46 61%

40 53%

37 49%

36 48%

27 36%

27 36%

23 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause hyperphosphataemia in dogs?: 75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 66 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

Hyperphosphataemia after Oclacitinib (Apoquel) 155 reports · 0.5% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with hyperphosphataemia