Hyperphosphataemia after Oclacitinib (Apoquel) in dogs

155 reports to the FDA describe hyperphosphataemia in dogs given Oclacitinib. That is 0.5% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

155Reports

68%Marked serious

4.5%Recovered

33%Died or euthanised

66 daysTypical onset

How soon it started

Same day

10 9.3%

1–2 days

5 4.6%

3–7 days

5 4.6%

1–4 weeks

19 18%

Over a month

69 64%

How the animals did

Recovered

6 3.9%

Recovered with lasting effects

1 0.6%

Still unwell when reported

80 52%

Died

12 7.7%

Euthanised

39 25%

Not known

17 11%

Problems reported at the same time

130 84%

72 46%

71 46%

68 44%

51 33%

43 28%

42 27%

28 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause hyperphosphataemia in dogs?: 155 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 66 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

Hyperphosphataemia after Cyclosporine (Atopica) 75 reports · 0.5% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with hyperphosphataemia