Abnormal ultrasound finding after Cyclosporine (Atopica) in dogs

The FDA has received 200 reports of abnormal ultrasound finding in dogs after Cyclosporine. That is 1.3% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

200Reports
47%Marked serious
7.0%Recovered
29%Died or euthanised
27 daysTypical onset
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How soon it started

Same day
12 20%
1–2 days
3 5.0%
3–7 days
7 12%
1–4 weeks
10 17%
Over a month
28 47%

How the animals did

Recovered
11 5.5%
Recovered with lasting effects
3 1.5%
Still unwell when reported
34 17%
Died
32 16%
Euthanised
26 13%
Not known
94 47%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
11
4–7 years
59
8–11 years
79
12+ years
48

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause abnormal ultrasound finding in dogs?
200 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 27 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Cyclosporine in dogs · Medicines most reported with abnormal ultrasound finding