Abnormal ultrasound finding after Oclacitinib (Apoquel) in dogs

431 reports to the FDA describe abnormal ultrasound finding in dogs given Oclacitinib. That is 1.5% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

431Reports
64%Marked serious
4.4%Recovered
27%Died or euthanised
73 daysTypical onset
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How soon it started

Same day
13 4.5%
1–2 days
15 5.2%
3–7 days
16 5.6%
1–4 weeks
49 17%
Over a month
195 68%

How the animals did

Recovered
17 3.9%
Recovered with lasting effects
2 0.5%
Still unwell when reported
269 62%
Died
21 4.9%
Euthanised
94 22%
Not known
28 6.5%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
25
4–7 years
123
8–11 years
200
12+ years
78

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause abnormal ultrasound finding in dogs?
431 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 73 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with abnormal ultrasound finding