Abnormal radiograph finding after Cyclosporine (Atopica) in dogs

The FDA has received 259 reports of abnormal radiograph finding in dogs after Cyclosporine. That is 1.7% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

259Reports
46%Marked serious
4.6%Recovered
34%Died or euthanised
42 daysTypical onset
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How soon it started

Same day
16 22%
1–2 days
5 6.8%
3–7 days
6 8.2%
1–4 weeks
8 11%
Over a month
38 52%

How the animals did

Recovered
8 3.1%
Recovered with lasting effects
4 1.5%
Still unwell when reported
40 15%
Died
53 20%
Euthanised
36 14%
Not known
118 46%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
34
4–7 years
80
8–11 years
106
12+ years
37

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause abnormal radiograph finding in dogs?
259 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 42 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

All reported side effects of Cyclosporine in dogs · Medicines most reported with abnormal radiograph finding