Abnormal radiograph finding after Oclacitinib (Apoquel) in dogs

442 reports to the FDA describe abnormal radiograph finding in dogs given Oclacitinib. That is 1.5% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

442Reports
71%Marked serious
5.9%Recovered
29%Died or euthanised
71 daysTypical onset
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How soon it started

Same day
20 6.2%
1–2 days
22 6.8%
3–7 days
19 5.9%
1–4 weeks
62 19%
Over a month
201 62%

How the animals did

Recovered
22 5.0%
Recovered with lasting effects
4 0.9%
Still unwell when reported
265 60%
Died
30 6.8%
Euthanised
96 22%
Not known
25 5.7%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
38
4–7 years
119
8–11 years
199
12+ years
81

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause abnormal radiograph finding in dogs?
442 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 71 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with abnormal radiograph finding