Cough after Oclacitinib (Apoquel) in dogs

328 reports to the FDA describe cough in dogs given Oclacitinib. That is 1.1% of all reports for this medicine, compared with 0.8% across reports for all dog medicines.

328Reports

45%Marked serious

15%Recovered

8.8%Died or euthanised

32 daysTypical onset

How soon it started

Same day

37 15%

1–2 days

24 9.8%

3–7 days

27 11%

1–4 weeks

35 14%

Over a month

123 50%

How the animals did

Recovered

49 15%

Recovered with lasting effects

1 0.3%

Still unwell when reported

198 60%

Died

14 4.3%

Euthanised

15 4.6%

Not known

51 16%

Problems reported at the same time

Lethargy

71 22%

Loss of appetite

70 21%

Abnormal radiograph finding

65 20%

Vomiting

57 17%

Didn't work as expected

56 17%

Breathing problems

56 17%

Pneumonia

38 12%

Fever

31 9.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

119

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause cough in dogs?: 328 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 32 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cough with similar medicines

Cough after Cyclosporine (Atopica) 135 reports · 0.9% of its reports
Cough after Ilunocitinib (Zenrelia) 45 reports · 2.0% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with cough