Lufenuron + Milbemycin Oxime (Sentinel) side effects in Mastiffs

74 FDA reports involve Lufenuron + Milbemycin Oxime in a Mastiff. These are the problems they describe.

Didn't prevent heartworm
28 38%
Didn't stop worms
19 26%
Vomiting
14 19%
Lethargy
9 12%
Didn't work as expected
7 9.5%
Diarrhea
7 9.5%
Loss of appetite
5 6.8%
Itching
4 5.4%
Underdose
3 4.1%
Appetite loss
2 2.7%
Dry mucous membrane
2 2.7%
Didn't stop fleas
2 2.7%

All reports for Lufenuron + Milbemycin Oxime in dogs