Swelling after Emodepside + Praziquantel (Profender) in cats

86 reports to the FDA describe swelling in cats given Emodepside + Praziquantel. That is 1.5% of all reports for this medicine, compared with 1.9% across reports for all cat medicines.

86Reports

79%Marked serious

23%Recovered

27%Died or euthanised

1 daysTypical onset

How soon it started

Same day

30 43%

1–2 days

20 29%

3–7 days

12 17%

1–4 weeks

6 8.6%

Over a month

2 2.9%

How the animals did

Recovered

20 23%

Still unwell when reported

5 5.8%

Died

14 16%

Euthanised

9 10%

Not known

38 44%

Problems reported at the same time

24 28%

23 27%

19 22%

19 22%

17 20%

17 20%

15 17%

Application site reaction

14 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause swelling in cats?: 86 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Praziquantel 41 reports · 2.5% of its reports
Swelling after Praziquantel + Pyrantel 22 reports · 1.7% of its reports
Swelling after Pyrantel 23 reports · 4.1% of its reports

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with swelling