Hyperglycaemia after Emodepside + Praziquantel (Profender) in cats

49 reports to the FDA describe hyperglycaemia in cats given Emodepside + Praziquantel. That is 0.9% of all reports for this medicine, compared with 1.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

49Reports

69%Marked serious

29%Recovered

12%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 30%

1–2 days

17 43%

3–7 days

6 15%

1–4 weeks

3 7.5%

Over a month

2 5.0%

How the animals did

Recovered

14 29%

Still unwell when reported

7 14%

Died

3 6.1%

Euthanised

3 6.1%

Not known

22 45%

Problems reported at the same time

29 59%

22 45%

20 41%

17 35%

13 27%

13 27%

12 24%

9 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause hyperglycaemia in cats?: 49 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with hyperglycaemia