Hiding after Emodepside + Praziquantel (Profender) in cats

The FDA has received 154 reports of hiding in cats after Emodepside + Praziquantel. That is 2.7% of all reports for this medicine, compared with 2.4% across reports for all cat medicines.

154Reports

51%Marked serious

25%Recovered

9.1%Died or euthanised

Same dayTypical onset

How soon it started

Same day

63 52%

1–2 days

29 24%

3–7 days

17 14%

1–4 weeks

9 7.4%

Over a month

4 3.3%

How the animals did

Recovered

39 25%

Still unwell when reported

17 11%

Died

8 5.2%

Euthanised

6 3.9%

Not known

84 55%

Problems reported at the same time

64 42%

62 40%

41 27%

34 22%

31 20%

26 17%

24 16%

22 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause hiding in cats?: 154 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hiding with similar medicines

Hiding after Praziquantel 46 reports · 2.8% of its reports
Hiding after Praziquantel + Pyrantel 25 reports · 2.0% of its reports

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with hiding