Gagging after Emodepside + Praziquantel (Profender) in cats

The FDA has received 27 reports of gagging in cats after Emodepside + Praziquantel. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all cat medicines.

27Reports

48%Marked serious

44%Recovered

3.7%Died or euthanised

Same dayTypical onset

How soon it started

Same day

14 64%

1–2 days

5 23%

3–7 days

1 4.5%

1–4 weeks

2 9.1%

Over a month

0 0.0%

How the animals did

Recovered

12 44%

Still unwell when reported

3 11%

Died

1 3.7%

Not known

11 41%

Problems reported at the same time

9 33%

8 30%

7 26%

5 19%

4 15%

4 15%

4 15%

3 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause gagging in cats?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with gagging