Skin redness after Trilostane (Vetoryl) in dogs

The FDA has received 105 reports of skin redness in dogs after Trilostane. That is 0.9% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

105Reports

70%Marked serious

14%Recovered

11%Died or euthanised

29 daysTypical onset

How soon it started

Same day

6 6.8%

1–2 days

10 11%

3–7 days

10 11%

1–4 weeks

19 22%

Over a month

43 49%

How the animals did

Recovered

15 14%

Still unwell when reported

26 25%

Died

6 5.7%

Euthanised

6 5.7%

Not known

52 50%

Problems reported at the same time

29 28%

26 25%

24 23%

22 21%

20 19%

18 17%

17 16%

17 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause skin redness in dogs?: 105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 29 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin redness with similar medicines

Skin redness after Insulin 58 reports · 0.8% of its reports
Skin redness after Phenylpropanolamine (Proin) 212 reports · 5.1% of its reports
Skin redness after Levothyroxine 68 reports · 2.3% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with skin redness