Reddening of the skin after Trilostane (Vetoryl) in dogs

51 reports to the FDA describe reddening of the skin in dogs given Trilostane. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

51Reports

75%Marked serious

12%Recovered

5.9%Died or euthanised

27 daysTypical onset

How soon it started

Same day

5 11%

1–2 days

2 4.4%

3–7 days

4 8.9%

1–4 weeks

14 31%

Over a month

20 44%

How the animals did

Recovered

6 12%

Still unwell when reported

10 20%

Died

1 2.0%

Euthanised

2 3.9%

Not known

32 63%

Problems reported at the same time

Hair loss

17 33%

Skin rash or irritation

14 27%

13 25%

12 24%

11 22%

8 16%

7 14%

7 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause reddening of the skin in dogs?: 51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reddening of the skin with similar medicines

Reddening of the skin after Phenylpropanolamine (Proin) 54 reports · 1.3% of its reports
Reddening of the skin after Levothyroxine 44 reports · 1.5% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with reddening of the skin