Low thyroxine (t4) after Trilostane (Vetoryl) in dogs
The FDA has received 112 reports of low thyroxine (t4) in dogs after Trilostane. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.
112Reports
63%Marked serious
1.8%Recovered
11%Died or euthanised
126 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Trilostane treats Cushing's disease (an overactive adrenal gland).
Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Trilostane cause low thyroxine (t4) in dogs?
- 112 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 126 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Low thyroxine (t4) with similar medicines
- Low thyroxine (t4) after Levothyroxine 87 reports · 2.9% of its reports
All reported side effects of Trilostane in dogs · Medicines most reported with low thyroxine (t4)