Allergic reaction after Trilostane (Vetoryl) in dogs

53 reports to the FDA describe allergic reaction in dogs given Trilostane. That is 0.4% of all reports for this medicine, compared with 2.3% across reports for all dog medicines, so it is reported less often than average with this medicine.

53Reports
70%Marked serious
26%Recovered
11%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
11 24%
1–2 days
5 11%
3–7 days
4 8.7%
1–4 weeks
14 30%
Over a month
12 26%

How the animals did

Recovered
14 26%
Still unwell when reported
13 25%
Died
2 3.8%
Euthanised
4 7.5%
Not known
20 38%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
12
8–11 years
26
12+ years
13

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause allergic reaction in dogs?
53 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with allergic reaction