Abnormal ultrasound finding after Trilostane (Vetoryl) in dogs

457 reports to the FDA describe abnormal ultrasound finding in dogs given Trilostane. That is 3.8% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

457Reports
75%Marked serious
2.8%Recovered
23%Died or euthanised
50 daysTypical onset
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How soon it started

Same day
16 4.8%
1–2 days
16 4.8%
3–7 days
19 5.8%
1–4 weeks
86 26%
Over a month
193 58%

How the animals did

Recovered
9 2.0%
Recovered with lasting effects
4 0.9%
Still unwell when reported
96 21%
Died
25 5.5%
Euthanised
79 17%
Not known
244 53%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
36
8–11 years
225
12+ years
187

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause abnormal ultrasound finding in dogs?
457 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 50 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with abnormal ultrasound finding