Liver problems after Thyroxine in dogs

54 reports to the FDA describe liver problems in dogs given Thyroxine. That is 18% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports
54%Marked serious
9.3%Recovered
20%Died or euthanised
49 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
1 2.5%
1–2 days
3 7.5%
3–7 days
2 5.0%
1–4 weeks
12 30%
Over a month
22 55%

How the animals did

Recovered
5 9.3%
Still unwell when reported
26 48%
Died
2 3.7%
Euthanised
9 17%
Not known
12 22%

Problems reported at the same time

17 31%
17 31%
Abnormal ultrasound finding
11 20%
11 20%
Excessive urination
8 15%

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
6
8–11 years
27
12+ years
20

About this medicine

Type: medicine.

Questions owners ask

Can Thyroxine cause liver problems in dogs?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 49 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Thyroxine in dogs · Medicines most reported with liver problems