Unable to stand after Selamectin (Revolution) in dogs

39 reports to the FDA describe unable to stand in dogs given Selamectin. That is 0.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported less often than average with this medicine.

39Reports

62%Marked serious

23%Recovered

31%Died or euthanised

1 daysTypical onset

How soon it started

Same day

9 32%

1–2 days

11 39%

3–7 days

2 7.1%

1–4 weeks

2 7.1%

Over a month

4 14%

How the animals did

Recovered

7 18%

Recovered with lasting effects

2 5.1%

Still unwell when reported

10 26%

Died

4 10%

Euthanised

8 21%

Not known

8 21%

Problems reported at the same time

14 36%

12 31%

12 31%

10 26%

10 26%

7 18%

6 15%

6 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause unable to stand in dogs?: 39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to stand with similar medicines

Unable to stand after Ivermectin + Pyrantel (Heartgard Plus) 198 reports · 0.1% of its reports
Unable to stand after Milbemycin Oxime + Spinosad (Trifexis) 419 reports · 0.3% of its reports
Unable to stand after Moxidectin (ProHeart 6) 132 reports · 0.3% of its reports
Unable to stand after Milbemycin Oxime + Praziquantel (Interceptor Plus) 76 reports · 0.2% of its reports
Unable to stand after Milbemycin Oxime (Interceptor) 28 reports · 0.1% of its reports
Unable to stand after Ivermectin (Heartgard) 67 reports · 0.6% of its reports

All reported side effects of Selamectin in dogs · Medicines most reported with unable to stand