Eye or vision problems after Selamectin (Revolution) in dogs

126 reports to the FDA describe eye or vision problems in dogs given Selamectin. That is 0.4% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported less often than average with this medicine.

126Reports
23%Marked serious
7.1%Recovered
16%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
8 20%
1–2 days
13 33%
3–7 days
6 15%
1–4 weeks
8 20%
Over a month
5 13%

How the animals did

Recovered
7 5.6%
Recovered with lasting effects
2 1.6%
Still unwell when reported
25 20%
Died
19 15%
Euthanised
1 0.8%
Not known
72 57%

Problems reported at the same time

Age of the animals

Under 1 year
30
1–3 years
24
4–7 years
29
8–11 years
28
12+ years
11

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause eye or vision problems in dogs?
126 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eye or vision problems with similar medicines

All reported side effects of Selamectin in dogs · Medicines most reported with eye or vision problems