Liver problems after Same in dogs

34 reports to the FDA describe liver problems in dogs given Same. That is 38% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports
76%Marked serious
5.9%Recovered
29%Died or euthanised
112 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
0 0.0%
3–7 days
1 5.0%
1–4 weeks
4 20%
Over a month
15 75%

How the animals did

Recovered with lasting effects
2 5.9%
Still unwell when reported
11 32%
Died
4 12%
Euthanised
6 18%
Not known
11 32%

Problems reported at the same time

Loss of appetite
12 35%
10 29%
Death
10 29%
Kidney problems
9 26%
Lethargy
8 24%
Seizures
6 18%
Abnormal radiograph finding
4 12%
Fever
4 12%

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
1
8–11 years
12
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Same cause liver problems in dogs?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 112 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Same in dogs · Medicines most reported with liver problems