Restlessness or agitation after S-methoprene in dogs

194 reports to the FDA describe restlessness or agitation in dogs given S-methoprene. That is 12% of all reports for this medicine, compared with 1.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

194Reports
0.5%Marked serious
1.5%Recovered
0.5%Died or euthanised
–Typical onset
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How the animals did

Recovered
3 1.5%
Died
1 0.5%
Not known
190 98%

Problems reported at the same time

Age of the animals

Under 1 year
25
1–3 years
95
4–7 years
36
8–11 years
16
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can S-methoprene cause restlessness or agitation in dogs?
194 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of S-methoprene in dogs · Medicines most reported with restlessness or agitation