Lethargy after S-methoprene in dogs

547 reports to the FDA describe lethargy in dogs given S-methoprene. That is 33% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

547Reports
0.0%Marked serious
0.7%Recovered
4.4%Died or euthanised
–Typical onset
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How the animals did

Recovered
4 0.7%
Still unwell when reported
1 0.2%
Died
24 4.4%
Not known
518 95%

Problems reported at the same time

Age of the animals

Under 1 year
177
1–3 years
177
4–7 years
87
8–11 years
40
12+ years
20

About this medicine

Type: medicine.

Questions owners ask

Can S-methoprene cause lethargy in dogs?
547 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of S-methoprene in dogs · Medicines most reported with lethargy