S-methoprene side effects in dogs

1,638 reports sent to the FDA between 2000 and 2025 involve S-methoprene in dogs. The most reported problems were lethargy, vomiting, wobbliness (ataxia). 0.4% were marked serious.

1,638Reports
0.4%Marked serious
98%Only medicine involved
1.1%Recovered
2.4%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
1 0.1%

How soon problems started

Same day
9 33%
1–2 days
5 19%
3–7 days
2 7.4%
1–4 weeks
4 15%
Over a month
7 26%

Time from the first dose to the first sign, where both dates were reported (27 reports).

How the animals did

Recovered
18 1.1%
Still unwell when reported
7 0.4%
Died
39 2.4%
Not known
1,574 96%

Breeds named most often

Popular breeds appear more often because there are more of them.

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