Restlessness or agitation after Desoxycorticosterone Pivalate in dogs

The FDA has received 82 reports of restlessness or agitation in dogs after Desoxycorticosterone Pivalate. That is 2.5% of all reports for this medicine, compared with 1.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

82Reports

43%Marked serious

22%Recovered

13%Died or euthanised

25 daysTypical onset

How soon it started

Same day

7 21%

1–2 days

0 0.0%

3–7 days

3 9.1%

1–4 weeks

9 27%

Over a month

14 42%

How the animals did

Recovered

18 22%

Still unwell when reported

12 15%

Died

7 8.5%

Euthanised

4 4.9%

Not known

41 50%

Problems reported at the same time

22 27%

22 27%

21 26%

18 22%

17 21%

17 21%

16 20%

11 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause restlessness or agitation in dogs?: 82 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 25 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

Restlessness or agitation after Melarsomine (Immiticide) 679 reports · 3.0% of its reports
Restlessness or agitation after Polysulfated Glycosaminoglycan 126 reports · 2.3% of its reports
Restlessness or agitation after Diphenhydramine 167 reports · 3.5% of its reports
Restlessness or agitation after Butorphanol 130 reports · 2.9% of its reports
Restlessness or agitation after Cefpodoxime 111 reports · 2.7% of its reports
Restlessness or agitation after Tramadol 131 reports · 3.5% of its reports
Restlessness or agitation after Florfenicol + Mometasone + Terbinafine 80 reports · 2.3% of its reports
Restlessness or agitation after Propofol 60 reports · 2.0% of its reports
Restlessness or agitation after Dirlotapide 37 reports · 1.3% of its reports
Restlessness or agitation after Isoflurane 64 reports · 2.3% of its reports

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with restlessness or agitation