Restlessness or agitation after Cefpodoxime in dogs

The FDA has received 111 reports of restlessness or agitation in dogs after Cefpodoxime. That is 2.7% of all reports for this medicine, compared with 1.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

111Reports
37%Marked serious
29%Recovered
14%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
21 28%
1–2 days
16 21%
3–7 days
7 9.2%
1–4 weeks
17 22%
Over a month
15 20%

How the animals did

Recovered
30 27%
Recovered with lasting effects
2 1.8%
Still unwell when reported
29 26%
Died
7 6.3%
Euthanised
8 7.2%
Not known
35 32%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
15
4–7 years
29
8–11 years
36
12+ years
23

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause restlessness or agitation in dogs?
111 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with restlessness or agitation