Allergic reaction after Prednisolone + Trimeprazine in dogs

The FDA has received 63 reports of allergic reaction in dogs after Prednisolone + Trimeprazine. That is 3.0% of all reports for this medicine, compared with 2.3% across reports for all dog medicines.

63Reports
38%Marked serious
17%Recovered
4.8%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
14 34%
1–2 days
7 17%
3–7 days
1 2.4%
1–4 weeks
9 22%
Over a month
10 24%

How the animals did

Recovered
11 17%
Still unwell when reported
29 46%
Died
3 4.8%
Not known
20 32%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
19
4–7 years
21
8–11 years
16
12+ years
2

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone + Trimeprazine cause allergic reaction in dogs?
63 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

All reported side effects of Prednisolone + Trimeprazine in dogs · Medicines most reported with allergic reaction