Itching after Prednisolone + Trimeprazine in dogs

112 reports to the FDA describe itching in dogs given Prednisolone + Trimeprazine. That is 5.3% of all reports for this medicine, compared with 4.3% across reports for all dog medicines.

112Reports
33%Marked serious
33%Recovered
3.6%Died or euthanised
15 daysTypical onset
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How soon it started

Same day
16 20%
1–2 days
10 13%
3–7 days
6 7.6%
1–4 weeks
16 20%
Over a month
31 39%

How the animals did

Recovered
26 23%
Recovered with lasting effects
11 9.8%
Still unwell when reported
33 29%
Euthanised
4 3.6%
Not known
38 34%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
24
4–7 years
32
8–11 years
35
12+ years
10

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone + Trimeprazine cause itching in dogs?
112 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 15 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Prednisolone + Trimeprazine in dogs · Medicines most reported with itching