Appetite loss after Polysulfated Glycosaminoglycan in dogs

The FDA has received 51 reports of appetite loss in dogs after Polysulfated Glycosaminoglycan. That is 0.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

51Reports

47%Marked serious

37%Recovered

5.9%Died or euthanised

7 daysTypical onset

How soon it started

Same day

12 31%

1–2 days

3 7.7%

3–7 days

5 13%

1–4 weeks

9 23%

Over a month

10 26%

How the animals did

Recovered

19 37%

Still unwell when reported

11 22%

Died

1 2.0%

Euthanised

2 3.9%

Not known

18 35%

Problems reported at the same time

19 37%

18 35%

17 33%

7 14%

7 14%

6 12%

6 12%

5 9.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause appetite loss in dogs?: 51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Appetite loss with similar medicines

Appetite loss after Melarsomine (Immiticide) 24 reports · 0.1% of its reports
Appetite loss after Diphenhydramine 28 reports · 0.6% of its reports
Appetite loss after Tramadol 30 reports · 0.8% of its reports
Appetite loss after Florfenicol + Mometasone + Terbinafine 26 reports · 0.7% of its reports
Appetite loss after Famotidine 25 reports · 0.9% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with appetite loss