Medication error after Phenylpropanolamine (Proin) in dogs

The FDA has received 30 reports of medication error in dogs after Phenylpropanolamine. That is 0.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

30Reports
67%Marked serious
33%Recovered
13%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
8 42%
1–2 days
1 5.3%
3–7 days
1 5.3%
1–4 weeks
2 11%
Over a month
7 37%

How the animals did

Recovered
10 33%
Still unwell when reported
12 40%
Died
2 6.7%
Euthanised
2 6.7%
Not known
4 13%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
4
4–7 years
3
8–11 years
14
12+ years
9

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause medication error in dogs?
30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Medication error with similar medicines

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with medication error