Arthritis after Phenylpropanolamine (Proin) in dogs
The FDA has received 20 reports of arthritis in dogs after Phenylpropanolamine. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.
20Reports
95%Marked serious
5.0%Recovered
10%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Phenylpropanolamine treats urinary incontinence.
Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Phenylpropanolamine cause arthritis in dogs?
- 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Arthritis with similar medicines
- Arthritis after Trilostane (Vetoryl) 200 reports · 1.7% of its reports
- Arthritis after Levothyroxine 25 reports · 0.8% of its reports
All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with arthritis