Liver problems after Pantoprazole in dogs

138 reports to the FDA describe liver problems in dogs given Pantoprazole. That is 46% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

138Reports
96%Marked serious
4.3%Recovered
65%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
30 26%
1–2 days
23 20%
3–7 days
11 9.6%
1–4 weeks
22 19%
Over a month
28 25%

How the animals did

Recovered
6 4.3%
Still unwell when reported
31 22%
Died
28 20%
Euthanised
62 45%
Not known
11 8.0%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
22
4–7 years
44
8–11 years
43
12+ years
21

About this medicine

Type: medicine.

Questions owners ask

Can Pantoprazole cause liver problems in dogs?
138 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Pantoprazole in dogs · Medicines most reported with liver problems