Seizures after Ondansetron in dogs

The FDA has received 34 reports of seizures in dogs after Ondansetron. That is 5.1% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

34Reports
97%Marked serious
12%Recovered
59%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
5 19%
1–2 days
13 48%
3–7 days
1 3.7%
1–4 weeks
3 11%
Over a month
5 19%

How the animals did

Recovered
4 12%
Still unwell when reported
8 24%
Died
10 29%
Euthanised
10 29%
Not known
2 5.9%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
1
4–7 years
15
8–11 years
8
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause seizures in dogs?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with seizures