Loss of appetite after Ondansetron in dogs

The FDA has received 298 reports of loss of appetite in dogs after Ondansetron. That is 45% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

298Reports
83%Marked serious
9.4%Recovered
43%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
59 23%
1–2 days
46 18%
3–7 days
27 11%
1–4 weeks
52 21%
Over a month
69 27%

How the animals did

Recovered
28 9.4%
Still unwell when reported
108 36%
Died
38 13%
Euthanised
90 30%
Not known
34 11%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
48
4–7 years
89
8–11 years
91
12+ years
50

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause loss of appetite in dogs?
298 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with loss of appetite