Blood problems after Ondansetron in dogs

The FDA has received 105 reports of blood problems in dogs after Ondansetron. That is 16% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

105Reports
91%Marked serious
4.8%Recovered
53%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
14 15%
1–2 days
17 18%
3–7 days
16 17%
1–4 weeks
19 20%
Over a month
29 31%

How the animals did

Recovered
5 4.8%
Still unwell when reported
41 39%
Died
14 13%
Euthanised
42 40%
Not known
3 2.9%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
9
4–7 years
41
8–11 years
26
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause blood problems in dogs?
105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with blood problems